​HBOT has shown significant promise in improving symptoms associated with mild-to-moderate traumatic brain injury, including: Persistent headaches Cognitive deficits and brain fog Mood disorders Memory problems Post-concussion syndrome When the brain sustains a traumatic injury, certain regions experience reduced blood flow and oxygen supply. HBOT increases oxygen delivery to these affected areas, promoting cellular healing and reducing neurological inflammation. Research — including studies on military veterans with TBI — has documented measurable improvements in cognitive and neurological function following a structured HBOT protocol. Who this helps: Patients recovering from head injuries, car accidents, sports concussions, and blast injuries.

A stroke occurs when blood supply to part of the brain is cut off, causing brain cells in that region to die from oxygen deprivation. Some cells die immediately — but many enter a dormant state, still alive but non-functional due to lack of oxygen. HBOT works by flooding these oxygen-starved regions with high-pressure oxygen, reactivating dormant brain cells and stimulating the growth of new blood vessels around damaged areas. This supports neurological recovery and can restore function in areas previously thought permanently impaired. Dr. Jenkins has direct clinical experience as a stroke champion — under her leadership at Sinai-Grace Hospital, the facility became a Stroke Center of Excellence certified by the Joint Commission for Healthcare Accreditation. Who this helps: Patients in the recovery phase following ischemic or hemorrhagic stroke who want to maximize neurological restoration.

Alzheimer's disease and other forms of dementia are characterized by the progressive deterioration of brain regions responsible for memory, language, and cognitive function. A key driver of this deterioration is reduced oxygen supply to brain tissue. HBOT addresses this directly by re-oxygenating affected brain regions, slowing the pace of cognitive decline, and supporting the brain's natural repair mechanisms through neurogenesis — the growth of new neurons. At Associated NeuroRehab, we use validated clinical tools including the BrainCheck Cognitive Assessment and an Early Dementia Memory Test to monitor patient progress before, during, and after treatment. Who this helps: Patients with early to moderate Alzheimer's disease, vascular dementia, and age-related cognitive decline or accelerated memory loss.

Chronic inflammation is a persistent, low-grade inflammatory response that underlies many serious health conditions — from autoimmune diseases to cardiovascular disease and neurological disorders. HBOT reduces chronic inflammation through two key mechanisms: Decreasing the production of pro-inflammatory cytokines such as TNF-α and IL-6 Promoting anti-inflammatory pathways, including increased IL-10 activity By addressing inflammation at a cellular level, HBOT helps reduce systemic damage and supports the body's return to healthy function. Who this helps: Patients with systemic chronic inflammation, inflammatory conditions, and those whose other conditions are driven or worsened by persistent inflammation.

Migraines, particularly those with aura — are often linked to vascular changes in the brain, reduced oxygen supply to certain brain regions, and neurogenic inflammation. HBOT addresses all three of these mechanisms: Increased oxygenation — restores oxygen supply to brain regions affected during a migraine episode Anti-inflammatory effect — reduces neurogenic inflammation associated with migraine attacks Pain pathway modulation — influences neurotransmitter activity and reduces the central nervous system's perception of pain Vascular stabilization — helps stabilize the vascular changes that trigger or worsen migraine attacks Some studies have shown that HBOT can reduce both the duration and intensity of acute migraine attacks, with the best results seen when treatment is administered early in the migraine phase. Who this helps: Patients with chronic migraine, migraines with aura, and those who have not found adequate relief through conventional migraine treatments alone. Condition 6: Diabetes & Wound Prevention Heading: Diabetes & Diabetic Wound Care Content: One of the most serious complications of diabetes is the development of chronic wounds — particularly on the feet and lower extremities — that fail to heal due to oxygen deficiency in the tissue. Left untreated, these wounds can lead to infection, tissue death, and ultimately amputation. HBOT is one of the most effective interventions for preventing diabetic amputations. By flooding oxygen-deficient extremity tissue with high-pressure oxygen, HBOT: Stimulates the growth of new blood vessels in ischemic tissue Accelerates wound healing in tissue with compromised circulation Reduces infection risk in chronic non-healing wounds Prevents tissue death when intervention happens early enough Timing is critical. The sooner a diabetic patient with a wound reaches the chamber, the greater the chance of preventing irreversible damage. Early intervention is strongly encouraged. Who this helps: Patients with Type 1 or Type 2 diabetes who have chronic non-healing wounds, diabetic foot ulcers, or are at risk of amputation. Condition 7: Fractures & Sports Injuries Heading: Fractures & Sports Injuries Content: Whether from a sporting accident, trauma, or surgical procedure, fractures and musculoskeletal injuries require significant oxygen to heal. HBOT accelerates this healing process by: Increasing oxygen supply to injured bone and surrounding tissue Stimulating angiogenesis — the growth of new blood vessels that deliver nutrients to healing tissue Reducing post-injury inflammation that slows recovery Supporting faster return to full function after surgery or trauma Athletes at all levels — from recreational to professional — have turned to HBOT to shorten recovery timelines and return to performance sooner. Who this helps: Patients recovering from bone fractures, ligament injuries, muscle tears, post-surgical recovery, and sports-related musculoskeletal injuries. Condition 8: Anxiety & PTSD Heading: Anxiety & Post-Traumatic Stress Disorder (PTSD) Content: While research in this area is still emerging, HBOT has shown meaningful promise as an adjunctive therapy for anxiety and PTSD. The mechanisms through which it may help include: Improved brain oxygenation — enhances oxygen delivery to brain regions involved in mood regulation and anxiety management Reduction in inflammation — chronic inflammation is associated with anxiety disorders; HBOT reduces inflammatory markers that may contribute to symptoms Neurogenesis and brain repair — HBOT promotes the growth of new neurons and supports the repair of damaged brain cells, potentially restoring balance to neural circuits involved in anxiety Stress hormone regulation — some studies suggest HBOT can help modulate the hypothalamic-pituitary-adrenal (HPA) axis, which regulates stress responses and is often dysregulated in anxiety disorders Improved sleep quality — anxiety is frequently linked with sleep disturbance; HBOT may improve sleep patterns, indirectly reducing anxiety symptoms Increased energy and mental clarity — enhanced oxygenation can reduce feelings of overwhelm and mental fatigue associated with anxiety HBOT has also been explored for TBI-related PTSD in military personnel, with some reports of significant symptom improvement. Important note: HBOT should not replace established treatments such as psychotherapy or medication. It is best used as part of a comprehensive care plan. Consult Dr. Jenkins to determine whether it is appropriate for your situation. Who this helps: Patients with generalized anxiety disorder, PTSD, and anxiety associated with neurological conditions or trauma. Condition 9: Sickle Cell Disease Heading: Sickle Cell Disease Content: Sickle cell disease causes red blood cells to take on an abnormal crescent shape, making them prone to clumping together and blocking blood vessels — a painful and dangerous event known as a vaso-occlusive crisis. These blockages deprive tissues and organs of oxygen, causing severe pain and long-term organ damage. HBOT supports sickle cell patients by: Increasing dissolved oxygen in the plasma — independent of red blood cell transport Reducing the frequency and severity of pain crises Improving oxygenation of tissues affected by vaso-occlusive events Reducing inflammation associated with sickle cell complications Who this helps: Patients with sickle cell disease experiencing recurrent pain crises, chronic pain, or oxygen-deficiency complications. Condition 10: Cancer Support Heading: Cancer Support (Select Cancers) Content: HBOT is not a treatment for cancer itself, but it plays a meaningful supportive role in the healing and recovery of certain cancer patients — particularly those with oxygen-dependent cancers such as leukemia, where enhanced oxygenation aids cellular repair and supports the body's response to treatment. HBOT may also be beneficial for patients experiencing radiation tissue damage — an FDA-approved indication — where healthy tissue surrounding a treated area has been damaged by radiation therapy. Important note: HBOT for cancer support is condition-specific. Dr. Jenkins will assess your individual case to determine whether HBOT is appropriate as part of your overall care plan. Who this helps: Select cancer patients — particularly those with leukemia, radiation tissue damage, or oxygen-deficiency complications related to their condition or treatment. Condition 11: Severe Anemia Heading: Severe Anemia Content: Anemia — in any form — reduces the blood's ability to carry oxygen throughout the body, leaving tissues and organs chronically under-oxygenated. In severe cases, this oxygen deficit can cause significant damage to vital organs and the brain. HBOT bypasses the normal hemoglobin-dependent oxygen transport system by dissolving oxygen directly into the blood plasma. This means that even when red blood cell count or hemoglobin is severely reduced, the body can still receive the oxygen it needs to function and heal. Who this helps: Patients with any form of severe anemia — including iron-deficiency anemia, aplastic anemia, hemolytic anemia, and anemia associated with chronic disease. Condition 12: Autoimmune Diseases Heading: Autoimmune Diseases Content: In autoimmune conditions, the immune system mistakenly attacks the body's own healthy tissue — driving chronic inflammation, oxidative stress, and progressive organ damage. HBOT addresses several of the underlying mechanisms of autoimmune disease: Immune modulation — HBOT promotes regulatory T-cell (T-reg) activity, which helps suppress overactive immune responses typical in autoimmune conditions Reduction in inflammation — decreases pro-inflammatory cytokines (TNF-α, IL-6) while increasing anti-inflammatory cytokines (IL-10) Reduced oxidative stress — lowers reactive oxygen species (ROS) production, which plays a role in autoimmune disease progression Tissue healing — enhances oxygen delivery to inflamed and damaged tissue, supporting repair Conditions where HBOT has shown early promise include rheumatoid arthritis, inflammatory bowel disease (Crohn's disease and ulcerative colitis), systemic lupus erythematosus, and multiple sclerosis. Important note: HBOT is not a cure for autoimmune diseases and should be used as part of a comprehensive management plan. Dr. Jenkins will assess your individual condition before recommending a protocol. Who this helps: Patients with rheumatoid arthritis, lupus, Crohn's disease, ulcerative colitis, and other autoimmune conditions characterized by chronic inflammation. Condition 13: Multiple Sclerosis (MS) Heading: Multiple Sclerosis (MS) Content: Multiple sclerosis is a chronic autoimmune condition in which the immune system attacks the myelin sheath — the protective coating surrounding nerve fibers in the central nervous system. This causes progressive neurological symptoms including fatigue, spasticity, cognitive changes, and loss of coordination. HBOT may support MS patients through several mechanisms: Reduced inflammation — oxygen therapy promotes an anti-inflammatory environment in the CNS Improved neural repair — enhanced oxygen levels may support myelin repair and cellular regeneration Reduced fatigue — one of the most commonly reported benefits among MS patients who undergo HBOT Improved circulation — enhanced blood flow and oxygenation in the brain and spinal cord supports overall CNS health Enhanced immune regulation — by reducing oxidative stress, HBOT may contribute to better immune system regulation Important note: Research results for HBOT in MS are mixed, and it is not a standard treatment for altering disease progression. It is best explored as part of a broader MS management plan under physician guidance. Who this helps: MS patients seeking symptom relief — particularly those experiencing fatigue, cognitive changes, or neurological symptoms that affect daily function. Condition 14: Burns & Skin Conditions Heading: Burns & Skin Conditions Content: Burn injuries damage or destroy skin and underlying tissue, creating oxygen-deficient wounds that are highly vulnerable to infection and slow to heal. HBOT accelerates burn wound recovery by: Saturating damaged tissue with oxygen, creating an environment hostile to anaerobic bacteria Stimulating angiogenesis — the growth of new blood vessels that deliver nutrients to healing skin Reducing inflammation and swelling in burned tissue Minimizing scar formation by supporting healthy tissue regeneration Accelerating the overall healing timeline Who this helps: Patients recovering from thermal burns, chemical burns, and severe skin conditions with compromised tissue oxygenation. Closing CTA Section Headline: Not Sure If Your Condition Qualifies? Content: If your condition is not listed here, it does not mean HBOT cannot help. Call us at 248.208.9215 to speak directly with our team. Dr. Tessy Jenkins will personally assess your condition and advise whether hyperbaric oxygen therapy is appropriate for you. All appointments begin with a phone consultation. We are available Wednesday through Saturday, 9:00 AM to 5:00 PM. Same-day appointments are available. All content on this page is based on clinical documentation, research materials, and information provided directly by Dr. Tessy Jenkins, Board-Certified Neurologist and Clinical Neurophysiologist, Associated NeuroRehab, Southfield, Michigan.Sonnet 4.6Adaptive

One of the most serious complications of diabetes is the development of chronic wounds — particularly on the feet and lower extremities — that fail to heal due to oxygen deficiency in the tissue. Left untreated, these wounds can lead to infection, tissue death, and ultimately amputation. HBOT is one of the most effective interventions for preventing diabetic amputations. By flooding oxygen-deficient extremity tissue with high-pressure oxygen, HBOT: Stimulates the growth of new blood vessels in ischemic tissue Accelerates wound healing in tissue with compromised circulation Reduces infection risk in chronic non-healing wounds Prevents tissue death when intervention happens early enough Timing is critical. The sooner a diabetic patient with a wound reaches the chamber, the greater the chance of preventing irreversible damage. Early intervention is strongly encouraged. Who this helps: Patients with Type 1 or Type 2 diabetes who have chronic non-healing wounds, diabetic foot ulcers, or are at risk of amputation.

Whether from a sporting accident, trauma, or surgical procedure, fractures and musculoskeletal injuries require significant oxygen to heal. HBOT accelerates this healing process by: Increasing oxygen supply to injured bone and surrounding tissue Stimulating angiogenesis — the growth of new blood vessels that deliver nutrients to healing tissue Reducing post-injury inflammation that slows recovery Supporting faster return to full function after surgery or trauma Athletes at all levels — from recreational to professional — have turned to HBOT to shorten recovery timelines and return to performance sooner. Who this helps: Patients recovering from bone fractures, ligament injuries, muscle tears, post-surgical recovery, and sports-related musculoskeletal injuries.

While research in this area is still emerging, HBOT has shown meaningful promise as an adjunctive therapy for anxiety and PTSD. The mechanisms through which it may help include: Improved brain oxygenation — enhances oxygen delivery to brain regions involved in mood regulation and anxiety management Reduction in inflammation — chronic inflammation is associated with anxiety disorders; HBOT reduces inflammatory markers that may contribute to symptoms Neurogenesis and brain repair — HBOT promotes the growth of new neurons and supports the repair of damaged brain cells, potentially restoring balance to neural circuits involved in anxiety Stress hormone regulation — some studies suggest HBOT can help modulate the hypothalamic-pituitary-adrenal (HPA) axis, which regulates stress responses and is often dysregulated in anxiety disorders Improved sleep quality — anxiety is frequently linked with sleep disturbance; HBOT may improve sleep patterns, indirectly reducing anxiety symptoms Increased energy and mental clarity — enhanced oxygenation can reduce feelings of overwhelm and mental fatigue associated with anxiety HBOT has also been explored for TBI-related PTSD in military personnel, with some reports of significant symptom improvement. Important note: HBOT should not replace established treatments such as psychotherapy or medication. It is best used as part of a comprehensive care plan. Consult Dr. Jenkins to determine whether it is appropriate for your situation. Who this helps: Patients with generalized anxiety disorder, PTSD, and anxiety associated with neurological conditions or trauma.

Sickle cell disease causes red blood cells to take on an abnormal crescent shape, making them prone to clumping together and blocking blood vessels — a painful and dangerous event known as a vaso-occlusive crisis. These blockages deprive tissues and organs of oxygen, causing severe pain and long-term organ damage. HBOT supports sickle cell patients by: Increasing dissolved oxygen in the plasma — independent of red blood cell transport Reducing the frequency and severity of pain crises Improving oxygenation of tissues affected by vaso-occlusive events Reducing inflammation associated with sickle cell complications Who this helps: Patients with sickle cell disease experiencing recurrent pain crises, chronic pain, or oxygen-deficiency complications.

Anemia, in any form, reduces the blood's ability to carry oxygen throughout the body, leaving tissues and organs chronically under-oxygenated. In severe cases, this oxygen deficit can cause significant damage to vital organs and the brain. HBOT bypasses the normal hemoglobin-dependent oxygen transport system by dissolving oxygen directly into the blood plasma. This means that even when red blood cell count or hemoglobin is severely reduced, the body can still receive the oxygen it needs to function and heal. Who this helps: Patients with any form of severe anemia — including iron-deficiency anemia, aplastic anemia, hemolytic anemia, and anemia associated with chronic disease.

In autoimmune conditions, the immune system mistakenly attacks the body's own healthy tissue — driving chronic inflammation, oxidative stress, and progressive organ damage. HBOT addresses several of the underlying mechanisms of autoimmune disease: Immune modulation — HBOT promotes regulatory T-cell (T-reg) activity, which helps suppress overactive immune responses typical in autoimmune conditions Reduction in inflammation — decreases pro-inflammatory cytokines (TNF-α, IL-6) while increasing anti-inflammatory cytokines (IL-10) Reduced oxidative stress — lowers reactive oxygen species (ROS) production, which plays a role in autoimmune disease progression Tissue healing — enhances oxygen delivery to inflamed and damaged tissue, supporting repair Conditions where HBOT has shown early promise include rheumatoid arthritis, inflammatory bowel disease (Crohn's disease and ulcerative colitis), systemic lupus erythematosus, and multiple sclerosis. Important note: HBOT is not a cure for autoimmune diseases and should be used as part of a comprehensive management plan. Dr. Jenkins will assess your individual condition before recommending a protocol. Who this helps: Patients with rheumatoid arthritis, lupus, Crohn's disease, ulcerative colitis, and other autoimmune conditions characterized by chronic inflammation.

Multiple sclerosis is a chronic autoimmune condition in which the immune system attacks the myelin sheath — the protective coating surrounding nerve fibers in the central nervous system. This causes progressive neurological symptoms including fatigue, spasticity, cognitive changes, and loss of coordination. HBOT may support MS patients through several mechanisms: Reduced inflammation — oxygen therapy promotes an anti-inflammatory environment in the CNS Improved neural repair — enhanced oxygen levels may support myelin repair and cellular regeneration Reduced fatigue — one of the most commonly reported benefits among MS patients who undergo HBOT Improved circulation — enhanced blood flow and oxygenation in the brain and spinal cord supports overall CNS health Enhanced immune regulation — by reducing oxidative stress, HBOT may contribute to better immune system regulation Important note: Research results for HBOT in MS are mixed, and it is not a standard treatment for altering disease progression. It is best explored as part of a broader MS management plan under physician guidance. Who this helps: MS patients seeking symptom relief — particularly those experiencing fatigue, cognitive changes, or neurological symptoms that affect daily function.

Burn injuries damage or destroy skin and underlying tissue, creating oxygen-deficient wounds that are highly vulnerable to infection and slow to heal. HBOT accelerates burn wound recovery by: Saturating damaged tissue with oxygen, creating an environment hostile to anaerobic bacteria Stimulating angiogenesis — the growth of new blood vessels that deliver nutrients to healing skin Reducing inflammation and swelling in burned tissue Minimizing scar formation by supporting healthy tissue regeneration Accelerating the overall healing timeline Who this helps: Patients recovering from thermal burns, chemical burns, and severe skin conditions with compromised tissue oxygenation.

HBOT is not a treatment for cancer itself, but it plays a meaningful supportive role in the healing and recovery of certain cancer patients — particularly those with oxygen-dependent cancers such as leukemia, where enhanced oxygenation aids cellular repair and supports the body's response to treatment. HBOT may also be beneficial for patients experiencing radiation tissue damage — an FDA-approved indication — where healthy tissue surrounding a treated area has been damaged by radiation therapy. Important note: HBOT for cancer support is condition-specific. Dr. Jenkins will assess your individual case to determine whether HBOT is appropriate as part of your overall care plan. Who this helps: Select cancer patients — particularly those with leukemia, radiation tissue damage, or oxygen-deficiency complications related to their condition or treatment.